"The usage that's coming is the usage of its time".
There are two major microarray platforms that have been widely used: cDNA microarrays and oligonucleotide microarrays.
Here, we have presented a novel 244 k microarray that is capable of measuring alternative promoter usage in over 34,000 putative promoters from nearly 7,000 genes.
Q. ARE YOU USING THE SAME TECHNOLOGY TO STUDY MALARIA? A. Yes, we use DNA microarrays that are similar to the virus chips.
It is now possible to apply microarrays beyond the conventional usage, proving that this technique can be flexible, however one has to be careful and respect the limits of cross-species hybridization.
One example: Corning is developing a protein array, made in a manner similar to the DNA Microarray, that can be used to check the potential of various substances for use as drugs.
But we could not get enough neoblasts for microarray, and that is why we chose tissues near the wounds for microarray analysis instead.
The hybridization patterns of the microarray indicated that Microbacteriaceae was present in PHS (Fig. 3a).
There are also entirely new approaches, like genetic microarrays that detect precancerous genes in breast tissue; identification of tumor markers -- proteins that appear on the surface of some cells; and blood tests that might detect secretions from cancerous cells.
Both sides have been helped by a technical development, the construction by companies like Affymetrix and Illumina of instruments known as microarrays or chips that can now detect up to 500,000 snips.
