Your English writing platform
Free sign upExact(1)
Because we intended to calculate the probability of any abnormal pediatric phenotype when the CNV was identified on prenatal microarray testing, we defined the frequency of disease (P(D)) to be 5.12%, which is derived from the work of Baird et al., who estimated the population frequency of diseases with an important genetic component among individuals younger than 25too be 53 in 1,000.
Similar(59)
Microarray testing was done in two batches but we found no evidence for a batch effect in our analyses.
To determine the level of agreement in the list of genes found differentially expressed with the microarray platforms tested, we analysed both fold changes and p values for genes showing the most significantly altered expression.
In a validation trial of a DNA microarray test for chlamydiae we repeatedly observed false-positive PCR amplicons from truly negative samples and non-template controls.
Whether microarray testing will become a standard is still unclear.
The window of opportunity for microarray testing might also be limited.
Insurance does not always pay for microarray testing since it is not considered the standard of care for prenatal testing.
"There definitely are complicated things you run into," said Dr. Arthur L. Beaudet, chairman of molecular and human genetics at Baylor College of Medicine, which offers microarray testing through its laboratory.
Although gene expression profiling using microarray technology is widely used in research environments, adoption of microarray testing in clinical laboratories is currently limited.
In the future, polymerase chain reaction assays, microarray testing, genomic analysis, and metabolic profiling will be accomplished in a rapid, portable, sensitive, and cost-efficient manner.
Only samples previously tested with the Versant™ HCV assay were available for microarray testing.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com