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Microarray techniques allow to detect genome-wide perturbations during various treatments and to measure various responses by multitude of gene probes.
Microarray techniques allow simultaneous measuring of the expression of thousands of genes under different experimental environments and conditions.
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The newly available microarray technique allows us to compare the expression profiles of more than 1000 genes that are likely to be associated with oncogenesis in cells at different stages of malignant transformation induced by mycoplasmal infection.
Additionally, the functional assays performed using this practical microarray technique allowed the preliminary identification of several genes involved in the activation of apoptosis, both in tumor and in primary cells.
Studies in cancer have validated the effectiveness of the microarray technique, allowing identification of tumor subclasses and marker genes for diagnosis and treatment of the disease (DeRisi et al., 1996; Sorlie et al., 2001).
Both techniques allow an intraoperative cholangiogram.
Tissue microarray (TMA) technique allows a simultaneous analysis of large amount of tumours on a single microscopic slide.
Another important assumption is forced by the massively parallel experimentation of the microarray technique which allows for assessing expression level of thousands of genes simultaneously.
Furthermore, unlike other current miRNA analysis techniques, microarrays allow fast analysis of miRNAs without an arbitrary preselection step.
The advent of omics technologies, such as gel- or mass spectrometry-based proteomics of the protein level and microarray techniques on the transcriptional level, allowed unbiased global analyses, searching for yet unknown differentially regulated proteins or transcripts under given experimental conditions.
This DNA microarray-based comparative genome sequencing technique allows high resolution detections of sequence polymorphisms [ 26- 28].
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