Although the use of different types of "normal" ovarian specimens makes comparison of our data with other studies difficult in most cases, in one microarray study, however, the normal control was human ovarian surface epithelial cells that had been immortalized using a retrovirus expressing human papillomavirus-derived viral oncoproteins E6 and E7 [40], [40].
Upregulation of mir32 in thyroid cancer vs. benign thyroid tumors has been detected in a microarray study; however functional implication of this microRNA in PTC is not known yet [ 50].
Many microarray studies, however, are performed with fewer than five samples in each group due to high-cost limitation or scarcity of biological source materials.
The four hypoxia-genes identified in our study have been found to be up-regulated by hypoxia in several microarray studies, however these findings were not validated e.g. by qPCR [ 27- 32].
Our findings of decreased COL9A1 expression in OA are consistent with recent proteomic (40) and microarray studies (41); however, other groups failed to observe this significant decrease in COL9A1 expression on gene profiling of OA (36, 42, 43).
Several of these genes have shown preferential expression in salmon peripheral blood leukocytes in previous microarray study [ 14]; however, their association with specific cell lineages remains unknown.
However, a microarray study utilizing pooled in vivo bovine embryos suggested that bovine EGA occurs between the 4- and 8-cell stages [ 11].
However, our microarray study did, whereas our RNA-seq study did not, identify IGFBP2 and IGFBP3 (genes encoding IGF1 binding proteins) as SDE (≤2-fold) in SNEB cow liver.
However our microarray study had noted upregulated expression of SOD2 in LEC, limbus and cornea (table 3) ii) Self renewal is an important feature of SC maintenance, which isabsent in differentiated cells, weakly expressed in quiescent SC but significantly expressed in proliferating progenitor cells such as mesenchymal stem cells (MSC), [ 40], intestinal crypts and neural crest cells[ 41, 42].
However, in our microarray study, FADS2, but not FADS1, was identified as SDE.
However, in a microarray study of type I endometrial cancer biopsies, a decrease in CAV1 mRNA was reported when compared with control samples [ 22].
