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Microarray studies performed on bone marrow derived murine DCs incubated with Eclispe or 3R4F cigarette extracts showed identical genotoxic profiles.
In spite of these factors, a number of studies have also demonstrated reproducibility of microarray studies performed at different platforms and laboratories, though most used the same source of RNA for these analyses [29], [30], [31].
Rather, the many microarray studies performed using obesity models have repeatedly demonstrated that microarray analysis can successfully differentiate between preadipocytes and adipocytes, the various body fat depots in humans, and the cellular response of adipocytes to exogenous compounds [11].
It should also be noted that in two microarray studies performed in primary breast-tumor samples before and after 24 72 h after chemotherapy, the up-regulated number of genes is ca 20% of those observed in our study [57], [58].
AGB carried out the microarray studies, performed the biological interpretation of the data and drafted the manuscript.
Follistatin mRNA was markedly overexpressed in HCC cell line microarray studies performed in our own laboratory (unpublished data).
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It is consistent, however with results from a microarray study performed with total RNA from early stationary growing cells [12] and a previous promoter analysis [49].
Melanocytes also express two isoforms of p63 [118], but p63 expression is not reported in 57 out of 59 tumors in a tissue microarray study performed by Brinck et al. [119].
We applied CFA to a microarray study performed to investigate cisplatin resistance in four ovarian cancer cell lines, which only differ in their degree of cisplatin resistance.
The selection was based on the analysis of a microarray study performed between Arabidopsis gai-1 mutants and non- mutant (WT) plants treated with flg22 (GEO accession: GSE17464).
A previous microarray study, performed with such a strategy on 4500 Drosophila genes, analyzed changes in transcription induced by paraquat, which produces superoxide radical (O2-) intracellularly: 5.2% of the genes (n = 236) were found to be stress responsive.
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