However, while there have been microarray studies examining intracellular bacteria [23], [24], [25], none have compared the intracellular transcriptomes of H37Ra and H37Rv, strains that are well documented for their disparities in virulence.
Microarray studies examining the postinjury response of specific classes of CNS neurons have also demonstrated how critical the issue of timing is in regard to the regenerative response.
Microarray studies examining skin four hours after pathogen exposure did not identify any genes differentially expressed between Trout Lodge and Hofer strains (data not shown).
Despite this major difference in study interpretation and conclusion, all human microarray studies examining insulin resistance in skeletal muscle paint a remarkably similar picture - one of no striking change in protein coding mRNA abundance.
Microarray studies examining the effects of HgCl2 or MeHgCl on gene expression found differential expression of genes involved in the oxidative stress response, protein degradation, mitochondrial dysfunction, endoplasmic reticulum stress and phase II metabolism [ 21- 23].
Initial evidence that VEGF may play a role in these vascular anomalies came from microarray studies examining expression patterns in Gcdh−/− mouse brain that showed increased expression of VEGF [ 32].
A second biofilm microarray study examined biofilm responses to acid resistance and oxidative stress using wild type and single gene knockout mutant strains of E. coli [41].
One microarray study examined differential gene expression within A. millepora and found few differences between bases and tips of the branches.
Little is known about the role RnDR plays in SCN pathogenesis, however an earlier microarray study examined abaxial and adaxial soybean embryo expression profiles upon exposure to auxin 2,4-dichlorophenoxyacetic acid (2,4 D).
A recent tissue microarray study examined expression of a panel of 13 biomarkers (including ER, PR and HER2), in two independent case series and found that only Bcl-2 retained prognostic significance independent of NPI on multivariate analysis (Callagy et al, 2006).
