Sentence examples for microarray studies assessing from inspiring English sources

Previous microarray studies assessing altered biological pathways in psoriasis consistently showed that mRNA encoding the transcription factor GATA3 was significantly downregulated in lesional psoriatic keratinocytes, and was re-induced by successful therapy [4], [5].

We conclude that despite encouraging data from previous microarray studies assessing non-neural tissues, the lack of a convergent set of differentially expressed genes associated with SZ using fibroblasts and LCLs indicates the utility of non-neuronal tissues for detection of gene expression differences and/or pathways associated with SZ remains to be demonstrated.

While microarray studies assess gene expression levels by measuring hybridization intensities to the relevant probes [1], SAGE studies use portions of cDNA transcripts known as SAGE tags that are concatenated, cloned, and sequenced to provide a quantitative measure of the transcripts levels in the cell [2].

Although this microarray study only assessed a limited amount (1124 sequences) of E. albidus sequences we were able to retrieve 10 orthologous transcripts that show highly comparable significant gene regulation upon Zn exposure.

As in microarray studies, to adequately assess ASE for a particular transcript using RNA-Seq, there must be adequate coverage for both alleles of that particular gene.

For microarray studies, RNA integrity was assessed on a BioAnalyzer; all samples had a RNA Integrity Number RINN) ≥9.5 (Agilent Laboratories, Santa Clara, CA).

Detailed genetic examination, conventional karyotype, and microarray studies are necessary to assess anomalies that are not usually related to this syndrome [ 57].

Se-deficient treatment groups were included in these microarray studies in order to assess Se status across the full range from Se-deficient to toxic Se status, to further characterize the effect of Se deficiency on the transcriptome, and to be able to distinguish the effects of Se deficiency from Se excess.

This was true both for miRNAs assessed by microarray studies and also when we focussed on examining the levels of particular miRNAs and their precursors by RT-PCR.

However, EHEC O157∶H7 housekeeping genes were not assessed in previous microarray studies.

This also allowed us to assess the diversity among the surviving selected clones and assess the necessity of microarray studies.