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The overall main effect of age on microarray signatures, however, was clearly detectable and was subjected to further analysis.
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Only three genes were shared between the two microarray signatures.
This procedure identified RGS4, MCTP1, CD44 and XIST as common between the two microarray signatures.
The 70-gene microarray signature was superior to clinicopathological risk assessment in predicting all endpoints.
The Kayankaya series remained his signature, however.
However, the microarray gene signature expressed by tumors more prone to dissemination is present in bulk tumor tissue, suggesting that the majority of cells within a primary tumor must possess an inherent metastatic capacity.
There are multiple advantages to a microarray-based signature based on FFPE tissue.
However, microarray studies often generate gene signatures consisting of hundreds of genes, making it difficult to distinguish which gene expression features are critical.
Commitment requires more than just signatures and handshakes, however.
Public-key signatures are expensive however.
Microarray gene expression signatures have been reported to predict survival of cancer patients [6].
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