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This model prompted us to perform a microarray screen to search for nuclear-enriched non-coding RNAs, using XIST's properties as a guide.
In this study, we present a functionally based microarray screen to identify novel molecular markers of the node, AME, and DE.
The approach has been coupled to a high-throughput microarray screen to examine how rapamycin exposure impacts on the re-seeding of the polysomal transcript populations.
To elucidate the potential downstream target(s) regulated by Nox4, we performed a microarray screen to assess the transcriptomes of transgenic (tg) mouse hearts in which Nox4 was overexpressed.
Taken together, these results suggest that hESCs differentiating to DE significantly upregulate cell surface expression of the subunits that comprise the integrin receptors that bind FN and VTN, the two ECMP components that we identified in our cellular microarray screen to promote DE differentiation.
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However, few of these studies have tested the candidate genes identified from these microarray screens to support a causal relationship between gene expression and behavioural performance [16].
Microarray screening to identify RASSF2A target genes failed to detect induction of proapoptotic genes.
Collectively, these data support the use of antibody microarray screening to identify highly-specific scFv antibodies as an alternative to conventional ELISA.
Using the combination of proteomic and microarray screens to identify interactive partners and genetic analysis to confirm the functionality of such interactions, we have found that Wwox participates in common pathways with CG6439/isocitrate dehydrogenase (Idh) and Cu Zn superoxide dismutase (Sod).
It is interesting to note that the cartilage gene set taken from another published microarray screen failed to be significantly enriched in our growth plate comparisons [23].
A cohort of Day 3 vitrified embryos that had been diagnosed as abnormal due to the presence of only reciprocal aneuploid polar bodies was warmed, cultured to Day 5, biopsied and reanalyzed with the same single-nucleotide polymorphism (SNP) microarray screening technology to determine the ploidy status of the resulting embryos and the prevalence of PSSC compared with non-disjunction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com