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As public microarray repositories are constantly growing, we are facing the challenge of designing strategies to provide productive access to the available data.
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Motivation: Microarray results accumulated in public repositories are widely reused in meta-analytical studies and secondary databases.
The raw microarray data have been deposited in the Gene Express Omnibus microarray repository and are publically available under accession number GSE11498.
Our complete repositories are available.
Many journals now state that submission of original data, such as microarray results, into appropriate repositories is a requirement for publication[1].
In parallel, an unbiased co-expression analysis based on microarray data available in public repositories was carried out using the Genevestigator software.
GEO microarray array public repository was initially searched for microarrays in which global gene expression in normal breast epithelium was compared to that of cancerous breast tissue.
Widespread use of microarrays has generated large amounts of data, the interrogation of the public microarray repositories, identifying similarities between microarray experiments is now one of the major challenges.
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Thousands of microarray results are available in public repositories such as the Gene Expression Omnibus Edgarr et al., 2002) and ArrayExpress (Brazma et al., 2003).
Oncomine [ 22, 23] is a cancer microarray repository, containing >18,000 gene expression profiles from a diverse number of microarray studies.
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