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Microarray profiling uncovered 48 miRNAs displaying more than three-fold enrichment between two or more brain regions.
Microarray profiling uncovered a significant reduction of Foxo1 expression in diabetic Timp3 −/− mice compared to WT, along with FoxO1 target genes involved in autophagy, while STAT1, a repressor of FoxO1 transcription, was increased.
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Functional profiling uncovered both common and specific requirements to cope with different cell wall damages.
The nine profiles uncovered enhance the overall understanding of how Q&A sites work.
The microarray profiling was performed as described in our previous work (Wang et al. 2014).
Microarray profiling was performed by Cogenics (Morrisville, NC).
AA and TAC performed the microarray profiling.
This analysis confirmed the microarray profiling data (Supplementary Figures 2a f).
We conducted in-depth time-course microarray profiling.
Our microarray analysis uncovered correspondence between the hepatic gene expression profiles of GHRH-KO mice and mice carrying a liver-specific Keap1-KO mutation, suggesting that Nrf2 activity might be elevated in GHRH-KO mice.
PCA of all these microarray data uncovered three major paths of differentiation from undifferentiated ES cells in 3D transcript profile space (Fig. 1B; Supplementary Video S1).
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