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Recently we performed a cross-platform comparison between SAGE and DNA microarray profiles showing that the ESR1, GATA3, and MUC1 genes are very tightly co-expressed in breast carcinomas [ 3].
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In both cases, the microarray profiles show a significant bias for authentic neuronal transcripts as only 55% of all genes with expression patterns listed in WormBase are neuronal (Fig. 4) [See Additional file 4].
The present microarray profiles show the upregulation of four chemokines, namely CCL5, interferon-induced protein of 10 kDa IP-10/CXCL10 IP-10/CXCL10n-interferon-inducibleha chemoattractanT-cellAchemoattractantCXCL16.
Microarray profiling showed genes involved in inflammation and immune-regulation were altered.
Previous microarray profiling showed that Cd53 was significantly up-regulated in preadipocytes from obese human subjects (Nair et al., 2005).
Our microarray profiling showed that several of the genes responding to chronic exposure to all three arsenicals were involved in the regulation of signal transduction pathways.
While RNAi screens investigate the role of host genes in viral infections, microarray profiling shows the expression change of host genes in response to viral infections.
Later, a study examining global gene expression changes between the hemangioma growth phases by microarray profiling showed a reduction in PDGFR- β expression during the involutive phase.
Genome-wide microarray profiling showed that DNA methylation levels in the promoter regions of a number of genes responsible for embryonic development were decreased in the MRL/MpJ versus the reference C57BL/6 J strain [ 25].
Moreover, comparison of the microarray-based genomic profiles showed similarity between Xf strains 9a5c and Fb7, which is unexpected, given the geographical and chronological differences associated with the isolation of these microorganisms.
Moreover, the microarray-based genomic profiles showed similarity between Xf strains 9a5c and Fb7, which is unexpected, given the geographical and chronological differences associated with the isolation of these microorganisms.
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