In the present study, PNAC071 gene was shown to primarily express in old root, while microarray profiles indicated the highest transcript abundance in differentiating xylems.
Moreover, microarray profiling indicated that one of these activities might reflect differential expression of a coordinated transcriptional program associated with activated mesenchymal cells.
Recent comparison of data from transcript sequencing and microarray profiling indicates that alternative splicing is more frequent in higher eukaryotes.
Integrative genomic analysis pointed at genes involved in ubiquitylation pathway as candidate drivers, while microarray expression profiles indicated that FXR1 was one of three genes from the amplicon consistently overexpressed in lung squamous cell carcinoma [ 57, 58].
Microarray profiling studies indicate that ~1 10% of the genes expressed in a particular animal cell type undergo circadian fluctuations, demonstrating the strong influence of clocks in global gene expression [ 4- 6].
Bioinformatic analysis of human microarray gene expression profiles indicates that REGγ gene expression is also increased in most of these human cancers, providing new evidence that REGγ-proteasome pathway may be involved in the development of multiple cancers.
Microarray data profiling indicated that 116 lncRNAs (67 up and 49 down) and 260 mRNAs were highly differentially expressed with an absolute fold change greater than ten.
Comparison of this isogenic pair by microarray gene expression profiling indicated that higher levels of enzymes in the glutathione pathway corresponded to resistance to depsipeptide seen in the line derived after chemotherapy.
Microarray profiling studies also indicate an OxyR-independent overexpression of nrdHIEF in E. coli in response to hydrogen peroxide [17] and, more recently, Hautefort et al. ([46]) showed induced nrdHIEF transcription during the early stages of macrophage infection but not in epithelial cell lines, thus corroborating our findings.
Finally, microarray-based RNA profiling indicated complex regulatory responses to changes of iron availability in both the marine cyanobacteria Synechococcus sp. WH7803 (Gierga et al. 2012) and Prochlorococcus (Thompson et al. 2011).
