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Furthermore, the identity of the input populations and the performance of the microarray platforms were confirmed by correlating our mRNA expression profiles with those previously published in the differentiation map of (human) hematopoiesis (DMAP 12 (Supplementary Fig. 1d g).
Although 3′-biased gene expression microarray platforms were the first generation to have widespread availability, newer platforms are gradually emerging that have more up-to-date content and/or higher cost efficiency.
Agilent 8x60K microarray platforms were used for these transcriptome analyses (Xuan et al. 2013).
Third, two different microarray platforms were used in generating data for this study.
Four microarray platforms were used in this analysis including; Agilent, Illumina, Affymetrix Exon 1.0 ST, and M430 arrays.
Because several different microarray platforms were used in those cohorts, we ensured that the probes were matched to identical genes.
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The technical reproducibility of microarray platforms is well established.
An index of microarray platforms was compiled to aid in the comparison of microarray data.
Microarray platforms are capable of parallel genotyping of hundreds of thousands of SNPs in one measurement.
Another problem with microRNA microarray platforms is a divergence in the stringency of the detection call criteria.
The rmodel source code and extended gene annotations for 11 microarray platforms are available at http://harlequin.jax.org/rmodel.org/rmodel
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