Sentence examples for microarray platforms show from inspiring English sources

Sta RT-PCR, QuantiGene and the five microarray platforms show a fold change ranging from -1.49 and 1.04 for FURIN.

All of the five microarray platforms show negative fold changes with four of the platforms indicating a twofold or greater change.

All the expression datasets derived from microarray platforms show a similar level of RD (see the Methods for details) while, as expected, the SAGE dataset (composed by some 46,000 tags) has a significantly higher RD value.

Some early studies, comparing different microarray platforms, showed that commercial microarrays were typically more consistent than non-commercial microarrays [ 11, 13, 18].

Previous studies using different microarray platforms showed that only approximately 3% or less of the RNA isolated from the FFPE tissue are useful for cDNA synthesis, which is an important step for gene expression analysis on a microarray platform [ 3].

Although microarray platforms showed similar levels of concordance with the RNA-seq data, the next generation sequencing (NGS) technologies provided high sensitivity, specificity, and accuracy as compared to the microarray platforms [ 66].

The data from all four microarray platforms showed that RGS2 was significantly upregulated in malignant breast cancers compared with normal luminal cells (Affymetrix: 3.2-fold increase, P = 3.77 × 10-10; Agilent: 2.49-fold increase, P = 1.25 × 10-6; CodeLink: 3.02-fold increase, P = 2.14 × 10-10; brk IMAGE: 2.71-fold increase, P = 1.35 × 10-6).

A more recent investigation into stilbene synthase expression during grape ripening with the latest and most comprehensive microarray platform showed low expression of STSs in all stages of berry development until post-harvest [ 67], suggesting that the precise timing of berry harvest could be a vital determinant in stilbene, and thus resveratrol, content in wine.

Interestingly, while these three genes display discordance among the microarray platforms, all four quantitative platforms show comparable results.

When compared to two other oligonucleotide microarray platforms, Actichip showed similar sensitivity and concordant expression ratios.

The top 50 discriminator genes over all four microarray platforms are shown in Figure 3 (complete list is given as Additional file 9).