This microarray platform enables the simultaneous analysis of all human microRNAs by either fluorescent or electrochemical signals, and can be easily redesigned to include newly identified miRNAs.
We show that a high-sensitivity microarray platform enables analysis of SM tissue samples from individual donors and derived cultures at whole transcriptome level.
The use of microarray platforms has enabled a wider exploration of the potential association between gene expression patterns.
An additional microarray platform that enables the measurement of single-nucleotide polymorphisms (SNPs), copy number, loss of heterozygosity (LOH), and DNA methylation simultaneously is methylation SNP (MSNP) [ 44, 45].
Although microarray platforms do not enable direct comparison of intensities between genes, that limitation does not affect our approach since gene-to-gene variations in intensity are included in the β ij s.
Advances in microarray technology have enabled exon-specific microarray platforms, in which all known and predicted exons in the genome have hybridization probes.
It is our hope that future genome sequencing will enable the construction of more comprehensive microarray platforms for economically important aquaculture species, such as Atlantic salmon and rainbow trout.
This tool enables users to search across these four different rice oligo microarray platforms to determine which probes from each platform map to a common Osa1 Version 5 rice genome annotation locus.
Strategies to pattern biomolecules and small molecules have enabled the advancement of tissue engineering and genomics, fabrication of biodevices, development of microarray platforms for diagnostics and drug screening, and investigation of fundamental cellular behavior.
While considerable divergence across different microarray platforms has been observed in the past [ 16, 17], their current accuracy and reproducibility [ 18, 19] now enable reliable comparisons to be made today.
