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These microarray platforms differ in their probe design, hybridization protocol, labeling and production methods [4], [5].
Indeed, microarray platforms differ on numerous technological aspects including array format and fabrication, protocols and instrumentation, as well as computational and statistical tools.
Comparison of gene lists and error rates across these studies and with ours is hampered by the fact that the treatment regimens, response definitions, and microarray platforms differ and that the histological composition of the samples in most studies was not presented.
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Because the microarray platform differed among these four datasets, it is plausible that the composition of the gene list differs among these four species.
Unfortunately none of these studies are directly applicable to one of the most commonly used human transcriptomic microarray platforms, namely Affymetrix Gene 1.0 ST arrays, either because they do not use a random priming approach or because the design of the microarray platform differs substantially from Gene 1.0 ST arrays.
However, individual microarray platforms themselves differ substantially [ 42] and a multiplatform approach, as used here, clearly defines a robust DTET seen by every technology.
The party platforms differ on the issue.
As different microarray platforms have different approaches on how to sample the transcriptome, and about how to represent the concept of 'genes', the details may differ between different platforms.
Different microarray platforms employ different designs.
Several different microarray platforms are commercially available, differing with respect to the fabrication methodologies and length of the oligonucleotide probes.
The integrated analyses of transcriptomic data which had originated from different publications and/or from different microarray platforms provided clear evidence that acid induced stress differs from the general ESR and is much more diverse.
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