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The creation of a comprehensive consensus sequence database for Pinus species, the design and construction of a microarray platform from this database, and the use of this microarray platform to monitor and characterise the transcriptomic response of P. radiata saplings to ethephon will be described.
The present study has examined the efficacy of a polymer microarray platform to screen a library of polyurethanes for applications such as human skeletal progenitor cell isolation and surface modification of tissue engineering scaffolds to enhance skeletal cell growth and differentiation.
We used a custom, in-house manufactured miRNA microarray platform to profile the expression of miRNAs [23].
DArT is a hybridization-based genotyping technology which is currently implemented on the microarray platform to rapidly and simultaneously identify and type DNA polymorphism [5].
Previously, we described the first use of a human gene promoter tiling microarray platform to identify genome-wide DNA methylation patterns in a human breast cancer cell line model of metastasis [4].
In previous work we demonstrated the ability of pilot versions of the peptide microarray platform to identify novel ligands for a number of specific protein modules [11], [13] [15].
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Our studies demonstrate the value of cell microarray platforms to decipher the combinatorial interactions at play in stem cell niche microenvironments.
In other words, a similar level of repeatability would be a relative advantage of microarray platforms to the Taqman system.
The same approach can also be applied to other microarray platforms to allow better evaluation of the potential impact of these polymorphisms on microarray expression data.
This tool enables users to search across these four different rice oligo microarray platforms to determine which probes from each platform map to a common Osa1 Version 5 rice genome annotation locus.
Briefly, we undertook simultaneous high-resolution, whole-genome analyses using Affymetrix gene expression (U133) promoter (1.0R) and Copy Number Variation/Single Nucleotide Polymorphism (SNP 6.0) microarray platforms to correlate gene expression, epigenetic (DNA methylation), and gene copy number information.
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