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Although the Illumina microarray platform provides a larger number of technical replicates on each array (usually over 30 randomly distributed beads per probe), these replicates have not been leveraged in the current log2 data transformation process.
Our protein microarray platform provides a high-throughput, comprehensive analysis of the feline humoral immune response to natural infection with the alpha-proteobacterium B. henselae at an antigen-specific, sera-specific, and genome-wide level.
The DNA microarray platform provides a suitable high-throughput environment to determine a large number of traits within a single diagnostic test.
The gene expression results of eight out of ten genes were confirmed, which is in line with the consensus that the Affymetrix microarray platform provides a reliable platform to measure gene expression [ 34].
The microarray platform provides an alternative means for approaching this challenge – rather than type a particular allele by a single unique probe, an allele can be identified by a unique set of probes such that an allele can be distinguished from another allele by its pattern of hybridization.
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The Affymetrix promoter microarray platform provided near-total coverage of CpG-rich regulatory regions in the human genome, with the inclusion of more than 25,000 human promoter regions, including 1,300 cancer-related genes.
This platform comparison analysis suggests that use of multiple microarray platforms provides complementary data as every microarray platform detects a unique set of novel CNVs.
RNA-sequencing has inherent advantages over microarray platforms, providing greater representation and quantitation of the gene transcripts, and better discrimination between isoforms or closely related sequences [ 56].
The integrated analyses of transcriptomic data which had originated from different publications and/or from different microarray platforms provided clear evidence that acid induced stress differs from the general ESR and is much more diverse.
Mootha et al. [ 1] studied a group of older diabetes subjects (approximately 66 years) using a microarray platform that provides greater coverage of the transcriptome (approximately 20,000 sequences).
A powerful way to gain insight into the molecular complexity and pathogenesis of arthritis has arisen from oligonucleotide-based microarray technology [ 3], because this platform provides an opportunity to analyze simultaneously the expression of a large number of genes in disease tissues.
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