Sentence examples for microarray platform also from inspiring English sources

The choice of microarray platform also affects the possibilities to accurately identify differentially expressed genes.

Our microarray platform also contains 2376 AFAS probes designed to correspond to every 500 bases of the antisense strand of exonic regions of well-known genes suitable for cancer research to screen for transcripts originating from the antisense strand.

However a similar parametric analysis of data from a distinct microarray platform also results in the identification of a set of differentially expressed genes that dissimilar to a degree that is beyond what would be expected from false-positive errors alone.

The microarray platform also comprised 5028 probes for 1875 intragenic elements referred to as "gene-int" (e.g. slr0898-int1), probes for 1939 asRNAs transcribed from the complementary strand of protein-coding genes and referred to as "gene-as" (e.g. sll0247-as), as well as probes for 608 sRNAs originating from intergenic regions, referred to as "NC-X" (e.g. NC-1).

Genome sequencing can be utilised for detecting gene deletions and amplifications [ 13, 14] although alternative methods such as DNA microarray platforms also allow copy number variable regions of the genome to be robustly detected on a large scale.

A relatively novel platform for gene expression data is RNA Sequencing (RNA-Seq), which allows us to study the complete transcriptome in more detail and with more precise measurements in comparison with microarray platforms, also facilitating the discovery of novel genes [ 21].

It was anticipated that this study would serve not only to experimentally validate the microarray platform, but also shed light on the genotypic differences between the two streptomycete species, and also between the two strains of S. lividans.

Besides the DNA-based array assay, the microarray platform is also being rapidly expanded to include the analysis of other biomolecules such as proteins and carbohydrates.

We used the same amplification chemistry on other types of arrays, which harbor probes of the other orientation relative to the transcripts under interrogation (Affymetrix Mouse 430 2.0 arrays), and on this microarray platform we also obtained results that are highly comparable to those from standard processing (data not shown).

The choice of microarray platform may also affect gene detection rates.

The reliability and repeatability of this microarray platform was also evaluated by the correlations between the two biological replicates.