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However microarray performance is still limited by the background noise.
The impact of 'block effects' on RT PCR and microarray performance is only just coming to light (Penland et al, 2007; von Ahlfen et al, 2007), but may not be as problematic as feared especially considering that RT PCR (the gold standard assay for FFPET interrogation) has demonstrated reliable performance despite the presence of these factors.
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Microarray performance was assessed using relative log expression and principal component analysis.
Next, the effect of the vRNA-depletion on the microarray performance was studied.
The quality of the hybridization and overall microarray performance was determined by visual inspection of the raw scanned data to exclude artifacts, scratches and bubbles.
Another interesting measure of microarrays performance is their sensitivity in detecting relatively low fold changes.
Recently, a prominent study on how batch effect removal techniques could improve microarray prediction performance was published [ 8].
Process improvement in microarray assay performance was demonstrated using samples prepared from commercially available materials and two metrics - diagnostic performance and the reliable range of measurement.
Potential batch effects for culture date, RNA processing data and microarray performance date were corrected during the analysis, with no major effect on the analysis.
Performance is performance.
During the development of the yeast spotted cell microarray technique it was observed that better performance was achieved using microarray pins that had been "blunted" by repeated use in printing cDNA arrays.
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