Sentence examples for microarray methodology with from inspiring English sources

The sensitivity of the microarray methodology with respect to the known pathogenic mutations was defined as the proportion of true positives detected by the microarray, while the specificity was defined as the proportion of true negatives detected.

Recently next generation sequencing technology in combination with microarray methodology [ 16] has been demonstrated to be a fast and reliable tool for analysis of large genes such as NEB[ 15].

This type of analysis allows integration of the typical microarray methodology examining highly expressed genes with the systems biology approach of examining large numbers of genes, some of which may be expressed only at low levels despite their importance to a given pathway [ 28].

The major shortcomings of the present work are the experimental cDNA microarray methodology and the small sample size with relatively short follow-up time.

These observations are consistent with previous reports of gene expression profiling using microarray methodology [ 36], and provide validation of the RT-PCR assays.

The resolution of this microarray methodology is ∼15% in exon inclusion differences [15].

It has been demonstrated that classification gene sets are profoundly influenced by the microarray methodology, such as the microarray technique, microarray platform, and preprocessing methods [ 4- 8].

Several power calculations for microarray methodologies exist, consequently sample size was determined and compared with two power calculation approaches.

Thus, we propose that peptide microarray methodologies are a powerful new tool for elucidating molecular interactions at chromatin.

Co-regulation of DBI with lipid metabolism is found consistently in experiments representing the two current microarray methodologies, Affymetrix oligonucleotide arrays [ 21] and spotted two-color cDNA arrays [ 22] (Table 1).

We illustrate the application of the methodology with gene expression data obtained from various microarray experiments with different conditions and diseases.