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As shown in Figure 6, the expression patterns of the five genes examined (Lcn2, SOCS3, Ier3, Pfc and Pascin3) were in agreement with the microarray findings, indicating that these genes may impact the differential outcome of S. aureus infection and widespread parenchymal destruction in the brains of MyD88 KO mice.
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Microarray findings indicate GIPC1 suppression is associated with an enrichment of abnormally expressed genes within the integrin-mediated, RHO protein, JAK-STAT, EGF, Ras, TGFβ and WNT pathways (Table 2 and Figure S2).
Our microarray findings indicate that miR-29a had significantly different expression between the three strains (adjusted p = 0.0008) only in adipose tissue, and the expression of this miRNA across these strains followed a BN<GK<WKY pattern.
Microarray findings suggest GIPC1 is involved in adhesion and motility (Tables 1 and 2).
However, both our microarray and qRT-PCR findings indicate that miR-206 was strongly up-regulated in brain tissues of mice exposed to RDX.
These findings indicated that microarray analysis with the AB platform showed enough sensitivity to reveal a specific transcriptional program induced by HCV in replicon cells.
These findings indicate that gene microarray study alone may be insufficient and a more rigorous study involving proteomics experiments or antibody microarrays are necessary to validate the candidate markers at the protein expression level.
These findings indicated that the actinobacterial microarray has the potential for wide application to the monitoring of changes in actinobacterial communities in aquaculture environments.
These diverse findings indicate that comparative analyses of cancer microarray data can reveal interesting and undetected relationships across different cancer types/subtypes, thus providing useful guiding information for further investigation.
Those findings indicate that the data from different microarray assays are comparable enough to identify biological heterogeneity between distinct tumor types.
These findings indicate that a carrier design based on microarray analysis and the manipulation of intracellular trafficking constitutes a rational strategy for reducing the host immune response to NPs.
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