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In fact, whole-genome microarray experiments performed under such conditions (YPD medium) yielded few, if any, specific Mediator targets.
In this way, these data are not representative of typical microarray experiments performed in a research setting, such as those involving clinical samples [6], [7].
For further details on the statistical analysis of both SAP102 and PSD-95 mutants, see Tables 3 and 4. We also validated the microarray experiments performed in SAP102 and PSD-95 mutants by qRT-PCR.
We have also identified CaM as being important and regulated in the hypothalamus using a meta-type analysis of data from multiple goldfish microarray experiments performed across the seasonal breeding cycle.
We obtained published gene expression datasets for microarray experiments performed with D1 cells, dexamethasone (10−8 M), the live microorganisms Schistosoma mansoni (MOI 1∶200 parasites/cell) and Leishmania mexicana (MOI 1∶8) [30], [31], [31].
Although a transcriptional contribution from the stromal cell fraction is detectable in microarray experiments performed on bulk tumor, the gene expression differences between the distant metastasis and no distant metastasis group were mostly ascribed to the tumor epithelial cells of the primary breast tumors.
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The second reference gene was a gene encoding DNA Polymerase IV, which was used in Rhodococcus sp. RHA1, Rhodococcus jostii, and Rhodococcus erythropolis, and this choice was justified based on a microarray experiment performed in Rhodococcus sp. RHA119,20.
Furthermore, hybridization values for PrP were investigated in a microarray experiment performed on in vivo skin wounds.
CB carried out the microarray experiment, performed the statistical analysis and drafted the manuscript.
To our knowledge, this is the first microarray experiment performed in this context.
EHW carried out the animal trial and microarray experiment, performed the statistical analyses of all data except for the microarray experiment, and drafted the manuscript.
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