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Some basic issues of microarray experiments, including experimental design, data analysis, and gene validation, are also discussed.
JR and JL performed all microarray experiments including CGH and gene expression.
KYY and MRP performed the microarray experiments including all statistical and bioinformatic analyses.
GAP and DAM designed the microarray experiments including expression analysis pipeline, GAP participated in writing the manuscript.
Microarray experiments including labeling, hybridizations and data analysis (one sample per chip) were carried out according to the manufacturer's manual.
RM, SCS and SM carried out all DNA microarray experiments including RNA isolation and preparation of cDNA.
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Examples of temporal microarray experiments include studies of the cell cycles in yeast [1] and the circadian cycles in mice [2].
The microarray experiments included in these analyses are outlined in Table 1 (Additional file 2, Table S1).
We aggregated 2178 gene lists generated from microarray experiments included in Gene Expression Omnibus (GEO).
The microarray experiments included in this manuscript have been submitted to ArrayExpress: accession numbers E-MEXP-697 and E-MEXP-709.
Many microarray experiments include only a few replications, therefore, it is critical to improve the effect size estimation in meta-analytic procedure.
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