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Poor expressional correlation among the rest of the ERG orthologs also suggests that the corresponding proteins either have lost their ability to physically interact in order to form stable complexes, or they do so in conditions/moments not covered by the microarray experiments explored here.
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We have conducted two large-scale microarray experiments to explore mismatch oligonucleotide behavior with real sample mixtures under tiling-array conditions.
Here, we present the results of two large-scale microarray experiments to explore MM oligonucleotide behavior with real sample mixtures under tiling-array conditions.
Having seen the effect of Hcl1 on M. tuberculosis growth and cell morphology, we next performed microarray experiments to further explore the effects of Hcl1 on mycobacterial cells.
Similar experiments exploring the effects of defects on hybridization affinity, also on microarrays, indicated that hybridization is significantly less error-sensitive.
As well as being employed to study genome-wide transcript expression, microarray experiments have been tailored to explore aspects of evolutionary processes, such as domestication in Atlantic salmon.
This Database has collected results of 419 microarray experiments (7137 samples) performed by authors exploring various aspects of Arabidopsis biology.
Because qRT-PCR is used to validate the results of microarray experiments, we used TaqMan miRNA arrays to explore the correlation of arrays with qRT-PCR.
In the future, we will explore more the applicability of single channel microarray experiments as well as the related normalization and analytical issues in different biological contexts.
There are multiple ways to explore the biological significance of results obtained in microarray experiments.
Some meta-analyses of microarray experiments aim at identifying biomarkers with particular expression patterns instead of exploring all possible profiles [ 6, 7].
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