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Microarray experiments designed to identify genes differentially expressed in the E11.5 lung and trachea showed that melanoma inhibitory activity (Mia1) was expressed only in the lung.
HD carried out microarray experiments, designed the database, and developed the web interface and data analysis tools.
She plans to study this issue further in gene microarray experiments designed to more thoroughly characterize the inflammatory response involved, and to see whether the fish might actually metabolize and excrete the particles.
Microarray experiments, designed to identify genes differentially expressed in response to elevated temperature in Anthopleura elegantissima [ 34] or A. viridis (data not shown), revealed that ferritin genes might be induced in response to increases in reactive oxygen species following thermal stress.
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Although useful for investigating the accuracy of these bacterial amplification systems, the above experimental design examining unamplified and amplified RNA from the same source did not allow for a comparison of amplification methods in a microarray experiment designed to extract meaningful biological information.
The algorithm described above was applied to a microarray experiment designed to compare gene expression in human cells harboring either a cadherin-derived inhibitor (Cad5CD) of the β-catenin pathway, or a dominant-negative Tcf inhibitor (TcfDN) of the pathway [ 7, 8].
The other list we used was a set of 50 genes identified in a microarray experiment designed to find early embryonic downstream targets of skn-1, called sdz (s kn-1– dependent zygotic) genes, several of which are transcriptionally active in only MS and E descendents (R obertson et al. 2004).
JRS participated in microarray experiments, design and analysis.
The most widely used microarray experiment design includes the use of a reference standard.
JZ and ZH assisted microarray experiment design and analysis.
AT advised on the microarray experiment design and performed the statistical analyses of the microarray data.
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