Sentence examples for microarray experimental technologies from inspiring English sources
Thus, the authors have made an important, if tentative, contribution towards bridging the gap between emerging microarray experimental technologies and the bioinformatics tools needed to interpret their output.
Due to the advances in high-throughput experimental technologies, an increasing number of large-scale microarray studies have been conducted to identify ageing associated genes in human and model organisms [ 2- 7].
The recent advancement of experimental technologies such as chromatin immunoprecipitation followed by massively parallel DNA sequencing (ChIP-seq) [ 26] or microarray hybridization (ChIP-chip) [ 27] enables us to more accurately determine genome wide occupation of TFs.
The classes one-color microarray experimental process and two-color microarray experimental process also specialize DNA microarray experimental process.
The two experimental technologies available for large-scale gene expression analysis are: 1) DNA sequencing-based serial analysis of gene expression (SAGE) and expressed sequence tag (EST) approaches and 2) dot-blot based microarray analysis.
In the 1990s, DNA microarray or DNA chip as a novel biological experimental technology was developed, which enables the comprehensive measurement of the expression levels of hundreds of genes, simultaneously.
A powerful high-throughput experimental technology, called the transcription factor knockout microarray (TFKM) [ 8], is widely used to investigate the regulatory relationships between TFs and genes.
To date, Chromatin Immunoprecipitation coupled with microarray chip (ChIP-Chip) or deep sequencing (ChIP-Seq) is the predominant experimental technology for obtaining genome-wide maps of histone modifications.
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In this study, based on microarray technology and experimental approaches, we suggest that NLC1-C functions as a repressor to regulate the expression of miR-320a and miR-383 by binding to Nucleolin in the nucleus and in the cytoplasm, NLC1-C is the direct target of miR-320a and miR-383 in human spermatogenesis.
Some microarray technologies and experimental designs produce intensity values whose absolute values cannot always be compared directly from gene to gene.
