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The microarray datasets deposited at Gene Expression Omnibus (GEO ID: GSE58824) were associated with a recently published study by Song et al. (2014) in BMC Genomics.
As DER was derived from all available human microarray datasets deposited at GEO, it provided a comprehensive metric to measure the regulation diversity at expression level.
There are currently 41124 microarray datasets deposited in Array Express database in contrast to only 5745 RNA-sequencing experiments (accessed 01/03/2014).
Because the DER is derived from all available human microarray datasets deposited in NCBI's GEO database (http://www.ncbi.nlm.nih.gov/geo/), it provides a comprehensive metric to measure the regulation diversity of genes at the expression level [ 44].
Recent availability of comprehensive mouse cardiac hypertrophy microarray datasets, deposited in resources such as ArrayExpress [ 11] and Gene Expression Omnibus [ 12], makes it possible to investigate global molecular mechanisms of this phenotype.
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Both in utero (using embryonic heart tissues) and in vitro (using iPSCs and differentiated cells) microarray datasets were deposited to the NCBI Gene Expression Omnibus (GEO) database.
The microarray datasets were deposited in the GEO data repository (http://www.ncbi.nlm.nih.gov/projects/geo/index.cgi) (accession numbers GSE4771 and GSE4777).
The totally 39 microarray datasets were deposited as NCBI GEOGSE32630.
Reporting Standards: Standard used to collect data: Microarray datasets are deposited at NCBI GEO according to MIAME 2.0 standards.
All microarray datasets are deposited at the NCBI GEO database (http://www.ncbi.nlm.nih.gov/) under accession number GSE55114.
Affymetrix U133 series are among the most widely used microarray platforms with thousands of datasets deposited in the public databases.
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