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As predicted from the microarray dataset, all OsADF genes were predominantly expressed in rice spikelets, with the expression of OsADF1 the highest (Figure 1A and B, Additional file 5: Figure S4).
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On the other hand, if node k belongs to the silver standard but was not included in the microarray dataset, then all ingoing and outgoing edges of k were removed from the silver standard.
The imputed ratios of the microarray datasets are all less than 50%, it seems to be reasonable to assume the imputed dataset is good enough to analyze the gene regulatory network.
For each microarray dataset we selected all known miRNA host genes and calculated a correlation matrix based on their expression profiles.
We also used an independent microarray dataset (childhood T-ALL samples, GSE46170) to test the classification accuracies of our subnetworks.
For instance, no such separation exists for the microarray dataset Leukemia AML-ALL studied by Golub and coworkers [ 55].
The mean and standard deviation of the total difference metric values for a given microarray dataset are calculated for all genes.
We also attempted to compare the expression of genes represented in the floral transcriptome with the expression of their respective A. thaliana orthologs based on presence/absence of expression in the microarray dataset [ 22] including all flower developmental stages.
Estimation of Runx1 levels based on this microarray dataset confirmed its expression in all MEC subsets except in ALs.
ImmGen is a public data gene-expression repository consisting of whole-genome microarray datasets for nearly all characterized cell populations of the adaptive and innate immune systems [20].
To understand the dynamics of global gene expression during oligodendrocyte differentiation, we analyzed a comprehensive microarray dataset which included expression values of all transcripts during a detailed time course of oligodendrocyte progenitor differentiation.
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