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As a matter of fact, this method can be used to retrieve data from public microarray databases and perform comparisons at the pathway level.
PS generated using sBEFs can be useful as "barcodes" to classify experiments in microarray databases and clustering of sBEFs can be a useful way to query experiments in databases according to their similarity at a pathway level.
Thus, we propose to store PSs as an additional experimental annotation in the microarray databases and implement methods using pathway signatures to query experiments in public databases and concurrent analyses of subsets of experiments.
Relationships between MYBBP1A expression levels and breast cancer progression were examined using patient microarray databases and tissue microarrays.
Issues of experimental reproducibility have become increasingly important with the advent of microarray databases and repositories (e.g. ArrayExpress [ 1], GEO [ 3]), given the potential they offer for cross-experimental comparison and data mining.
Furthermore, the rapid growth of microarray databases and other post-genomic resources for plants besides Arabidopsis (e.g. [ 64- 66]) is providing many sources of association evidence to reinforce the approach that we have pioneered here.
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The expression data for AtNCX4 (At1g55720) was not available in the microarray database and hence could not be included in expression analysis under different stresses.
To better exploit the increasing amount of data available from genomic sequencing, microarray database and RNAseq, time-efficient methods for identification and validation of candidate genes are needed.
Data was Log2 transformed and normalized using Lowess subgrid normalization in GeneTraffic Microarray Database and Analysis System (Iobion Informatics).
Data was uploaded to the GeneTraffic Bioinformatics server with GeneTraffic microarray database and analysis software (Stratagene/Agilent Technologies, La Jolla, CA) for raw image analysis, filtering and processing.
Furthermore, from analysis of microarray database and immunohistochemical staining, we present predictions where GRP94 may play an important role in specific adult organ homeostasis and function.
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