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Moreover, in silico meta-analysis of Oncomine's cancer microarray database indicates that FOXF1 mRNA is overexpressed in a significant subset of colorectal adenocarcinoma tumors compared with normal colorectal tissue and other types of cancers.
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We found microarray data with significant p-values from the Oncomine database indicating that this gene is repressed in tumors of the adrenal gland and the bladder (not shown).
Indirect relationships were detected when the database indicated relationships between genes that were related through intermediate genes not present on the microarray platform.
Careful analysis of the alternative transcript data available through the LocusLink database indicated that for 10 of these 13 genes, different subsets of alternative transcripts may be recognized by microarray probe sets and qRT-PCR probes.
A well-designed microarray database can provide valuable information on gene expression levels.
Data were obtained from a microarray database (http://www.ricearray.org/expression/meta_analysis.shtml; accession number GSE21396; Cao et al. 2012).
Data were obtained from a microarray database (http://www.ncbi.nlm.nih.gov; accession number GSE19024; Wang et al. 2010).
However, designing an efficient microarray database with minimum space usage is not an easy task since designers need to integrate the microarray data with the information of genes, probe annotation, and the descriptions of each microarray experiment.
Raw microarray data are available at the GEO microarray database.
Microarray data was deposited in the NCBI microarray database Gene Expression Omnibus with the accession code GSE17568.
The L2L Microarray Database, accessible through a web portal [38], contains a collection of results derived from published microarray data.
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