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Exact(6)
Intriguingly, when analyzing the six-gene operon encoded in SPI-4 (siiABCDEF) [22], only the siiB, siiC and siiD genes showed a significantly decreased expression (2- to 7-fold) (the siiA gene could not be detected among microarray data, whereas siiE and siiF did not show any significant change).
Reinke et al. (2004) found 3145 germline RNAs in this manner from microarray data, whereas Wang et al. (2009) found 1063 using SAGE.
TIMP-1 expression was estimated to be, on average, 7 fold higher in hemangiosarcomas than in splenic hematomas based on microarray data, whereas RT-qPCR showed changes as large as +800 fold.
Most of the respondents from government regulatory (85%) and research (75%) sectors also felt that it would be beneficial to have a requirement to submit microarray data, whereas pharmaceutical (53%) and academic (50%) respondents were less convinced.
Additional file 3 provides annotated DE gene sets from statistical analysis of the microarray data; whereas Additional files 4, 5, 6 provide annotation, functional analysis and mapping of DE genes to biological functions and canonical pathways by IPA software.
The expression of 19 genes detected via qRT-PCR showed a pattern that was similar to that observed in the microarray data, whereas 4 genes (CsNOL, CsPAL, CsFNS, CsF3H) showed a different expression pattern.
Similar(54)
Second, most clinical variables are of a categorical type, or are discretized by the physician, whereas microarray data are continuous data.
Xia et al. (2007) initially generated microarray data from nine tissues, whereas Zha et al. (2009) considered only five of these tissues in their analyses of dosage compensation.
RNA-sequencing data were obtained for sexual development (Wang et al. 2014), whereas microarray data were utilized for colony development (Kasuga and Glass 2008) and a time course of conidiation (Greenwald et al. 2010).
PKC δ predominantly facilitates intrinsic- or mitochondrial-mediated cell death, whereas microarray data suggest that death receptor or extrinsic cell death pathways regulate the initial wave of apoptosis during involution.
The qRT-PCR data were normalized to the abundance of 5.8S rRNA, whereas the microarray data were normalized to the global abundance of all miRNAs detected by microarray.
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