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Our pathway analysis on microarray data supplies a good resource for examining whether Mib functions beyond Notch signaling and/or for testing what genes are involved in the tissue/organ mis-patterning caused by compromised Notch activity.
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Although the regulatory repertoire for Fur has not been mapped in S. solfataricus, the microarray data supplied an obvious list of genes to be tested.
Resulting microarray data are supplied in Additional file 3. Table 1 summarizes the numbers of gene transcripts detected from different samples.
Prior published microarray data were used as supplied, as processed lists or downloaded from GEO [ 23, 24].
We are grateful for Peter Burghout and Aldert Zomer for expert advice and supplying gene essentiality microarray data of the S. pneumoniae transposon mutant library assayed in the genomic array footprinting experiment.
These databases supply a useful tool for a global biological interpretation of microarray data.
All microarray data were normalized as in Townsend et al. (2003) using the online tool supplied by the Filamentous Fungal Gene Expression Database (Zhang and Townsend 2010).
Human microarray platform, GPL1528; human HCC microarray data, GSE1898; mouse microarray platform, GPL1529; mouse HCC microarray data, GSE1897.
Saldana, A.J. Java Treeview - extensible visualization of microarray data.
Impute: impute: Imputation for microarray data.
microarray data reproduced, but some concerns remain.
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