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As shown in Figure 10B, the RT-PCR results are in better agreement with the microarray data, suggesting their involvement in abiotic and/or biotic stress.
In the case of CYP17, its down-regulation was blocked by ZM (microarray data), suggesting that it may be regulated via ERs.
The fold changes of these genes based on the calculation from semiquantitative RT-PCR results were largely consistent with the microarray data, suggesting that the microarray data are reliable.
In the validation experiments, gene expression alteration of selected genes by real-time PCR showed a very high degree of correlation with the microarray data suggesting that the changes of expression observed by genechip are most likely real.
Thus, after examining the effect of genistein on prostate cancer cells, we selected miRNA-1260b, whosexpressionon was significantly downregulated by genistein based on microRNA microarray data, suggesting that miR-1260b is an oncogenic miRNA.
The ectopical expression of CDX2 has been reported in intestinal-type gastric adenocarcinomas (Almeida et al, 2003), and this is consistent with microarray data suggesting that a group of intestine-specific genes are upregulated in gastric adenocarcinomas (Hippo et al, 2002).
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Microarray data suggested 65 immune related genes were commonly affected in the three treatment regimens.
The analysis and verification of proteome microarray data suggested that Pat acetylated several bacterial TFs.
Yet, the microarray data suggest that Esrrb and Mef2c are also rod-enriched (Fig. 1G, K).
These microarray data suggest that TPL2 expression in the prostate is inversely regulated by testosterone at the transcriptional level.
The microarray data suggest a decrease in transcript levels after day 15 for most of the genes studied.
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