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Steps 3.3 and 3.4 extracted drug microarray and disease microarray data respectively.
A.K. and S.W. analysed mouse behavioural data and microarray data, respectively.
"*" and "**" indicates experimentally verified miRNA-mRNA and possible miRNA-mRNA candidates revealed by microarray data, respectively.
Quantile normalisation was applied to mRNA and miRNA microarray data, respectively (see Methods).
Next, we applied the SIG++ method and permutation method to the microarray data, respectively, and detected the miRNA — mRNA pairs with significant regulation change.
The overall concordance of protein with transcript data was low with a Pearson's correlation of 0.27 and 0.24 for the RNAseq and microarray data, respectively.
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AV and AW performed the modeling and microarray data analysis, respectively.
In the section ' FIRST IRCCC Algorithm: BiBinCons ', we develop two IRCCC algorithms of biclustering of binary microarray data, called respectively BiBinCons and BiBinAlter.
We found 1,418 and 885 genes expressed in only one of 18 tissues from microarray and EST data, respectively.
Overall, for the abundance of the 1201 proteins identified, 24 and 33 % had a significant correlation with their transcript abundance for microarray and RNAseq data, respectively.
To estimate the possible range of regression variances, we estimated the sample variance components of the first two samples, and of the first and the last samples in the microarray time-course data respectively.
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