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By re-analyzing a dataset of microarray data derived from islets of type 2 diabetes patients (Dominguez et al., 2011), we found that rab1a mRNA expression was significantly decreased (P < 0.001, Fig. S1A).
Since few data are available on T cell lymphomas, we used microarray data derived from studies conducted on leukemia, lymphoma and myeloma samples (see Materials and Methods).
Therefore, it is not easy to correlate the microarray data derived from planktonic cultures with the increased biofilm production of the RND-mutants, with respect to the wild-type.
As Cldn13 appears to be preferentially expressed in tissues associated with haematopoiesis/immunity (bone, spleen and thymus) we analysed microarray data derived from mice exposed to the pathogenic protozoan T. congolense to determine whether Cldn13 levels were affected.
Human mouse and rat microarray data derived from 30 Affymetrix microarray platforms (Supplementary Table S1) were downloaded from the GEO ftp site and retrieved in seriesMatrix file format (ftp://ftp.ncbi.nih.gov/pub/geo/DATA/SeriesMatrix/).nih.gov/pub/geo/DATA/SeriesMatrix/
An outline of the data analysis workflow is shown in Fig 2. Quality control protocols for Affymetrix microarray data derived from human postmortem brains were applied as previously described [24], and samples which did not pass were removed from the dataset.
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In this retrospective study we compare microarray transcriptomic data derived from two different hESCs lines (HUES1 and H9) exposed to valproic acid (VA) while applying the same differentiation protocol.
To characterize the expression profiles of the FLAG MKRN1 RIP data set, the 3,192 unique transcripts comprising this data set were mapped onto microarray expression data derived from undifferentiated ESC populations.
Currently, one major drawback when performing microarray analyses on data derived from dietary intervention studies is the lack of proper statistical tools.
CNS [ 33] developed a classification system based on DNA microarray gene expression data derived from patient samples of Embryonal tumors of the central nervous system (CNS).
Microarray data were derived from custom microarray patterns, with probes placed in every exon and exon-exon junction, and a random-priming amplification protocol (Materials and Methods).
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