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This approach will be increasingly useful to discover diagnostic signatures as the mass of microarray data continues to grow in the 'omics' era.
Nonetheless, this approach will be increasingly useful to discover putative diagnostic signatures as the mass of microarray data continues to grow in the 'omics' era.
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The computational demand of analyzing these data continues to increase due to the reduced cost of microarrays and increases in the number of replicates being measured.
Despite the clear advantages of the factorial analysis of microarray data, the false discovery rate (FDR) continues to be a problem that cannot be ignored [ 26].
Other statistical tests continued to arise for use on microarray data, including but not limited to ANOVA [ 27] and RVM [ 28].
microarray data reproduced, but some concerns remain.
This push towards the direct comparison of microarray data from distant sites and dissimilar platforms is likely to continue.
It should be noted, however, that the QPCR data suggest NRG1 expression levels continue to decrease after adolescence, whereas the microarray data indicates a plateau effect.
The responses indicate that a lack of standardization will continue to represent a barrier to sharing microarray data and to the development of public databases.
The microarray data generated by Brunskill et al. (Brunskill et al., 2008) will allow continued bioinformatic interrogation for a number of purposes.
Human microarray platform, GPL1528; human HCC microarray data, GSE1898; mouse microarray platform, GPL1529; mouse HCC microarray data, GSE1897.
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