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The S. cerevisiae microarray data compendium [ 10] contains expression profiles for 6153 genes in 173 different stress conditions.
The E. coli microarray data compendium [ 2] contains expression profiles for 4345 genes under 189 different stress conditions and genetic perturbations.
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We also analyzed a compendium microarray data set from heart tissues of Mus musculus to evaluate the efficiency of the DeGNServer.
In order to account for the dynamic properties of proteins as well as their dynamic relationship with their neighbors in the network, we used gene expression information from a large compendium of microarray data and a high quality collection of protein interaction data to derive 9 network metrics that describe the dynamic behavior of a protein and of its neighborhood in the network (see Methods).
Within this framework, modules are extracted based on relevant gene sets from a compendium of microarray data.
We assembled a compendium of microarray data from 12 studies that measured host transcription in mouse lungs following infection with respiratory viruses (Table 1).
With this objective in mind, we developed two analyses showing how easy and quick meta-analysis can produce novel biological insights from the large compendium of microarray data.
In a recent study, we conducted a probabilistic inference of modulator activity on RelA activity using experimentally determined protein-protein interactions integrated with ChIP-Seq and a compendium of microarray data.
The module-mapping method of Segal et al. identifies modules of co-expressed genes from microarray data based on co-expression within the compendium and co-membership in previously annotated gene sets [ 27].
It unifies a large compendium of other published cancer microarray data, including Gene Expression Omnibus (GEO) [19] and Stanford Microarray Database (SMD) [20], and uniquely provides differential expression analyses comparing most major types of cancer with their respective normal tissues.
We developed a custom nCounter® malaria parasite gene probe set containing 328 genes, which were selected from a compendium of preexisting malaria expression microarray data sets (Methods).
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