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Arisi, I. et al. Gene expression biomarkers in the brain of a mouse model for Alzheimer's disease: mining of microarray data by logic classification and feature selection.
A new schema is proposed to store microarray data by using array data type in an object-relational database management system PostgreSQL.
After analyzing the microarray data by MetaCore™ algorithm, a total of 12 regulatory pathways were found to be associated with invasive phenotype (p < 0.001).
Fig. 2 Validation of microarray data by quantitative RT-PCR.
Validation of microarray data by qRT-PCR in mungbean seedlings.
The paper entitled "Detect key genes in classification of microarray data" by Yihui Liu addresses detection of key information from high-dimensional microarray profiles using wavelet analysis and genetic algorithm.
In their paper, the authors applied this idea to microarray data by [4].
Another measure for reliability is the independent verification of DNA microarray data by quantitative RT-PCR.
To validate microarray data by independent means, we have performed quantitative RT-PCR.
We validated our microarray data by performing real-time quantitative PCR on a subset of ORGs from independently derived biological samples.
We next confirmed the microarray data by quantitative RT-PCR for seven selected transcripts that were found down-regulated in the microarray analysis (FIGURE 2C).
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