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Surprisingly, microarray clustering showed F1 male profile as closest to F1 female and F0 male profile closest to F2 male.
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The analysis of gene expression by use of whole genome microarray and clustering showed that 882 genes were downregulated and 505 genes were upregulated after exposure to s-v.
In this analysis, the hiPSCs were clearly distinct from their parental SCs, and the dendrogram of the lectin microarray generated by unsupervised hierarchical clustering showed a clear separation between the hiPSCs and the parental SCs (Fig. 5A).
Previous microarray cluster analysis has shown that MCF-7 cells are characterized by high expression of genes associated with luminal epithelial cells, including the estrogen receptor and that this cell line is an acceptable model for the ER+/ERBB2- luminal tumors [ 22].
The heatmap of the RMA expression values from the microarray analysis showed clustering of the transcriptomes into groups formed by the three wild-type and two out of three Frzb-/ mice, respectively.
For example, the time to complete the smallest dataset (10 000 gene real microarray data) with k = 4 clusters shows a significant difference between the two versions of Cluster (5X faster than v2 and 12X faster than v3), but no difference between the R functions.
To date, a few clustering algorithms designed to exploit the digital data structure have been developed for SAGE data analysis, and shown to perform favorably compared to conventional microarray clustering algorithms [12].
For example, in one study involving microarray clustering, higher resolution clusters are in general subsets of lower resolution clusters [ 30].
#cluster shows the number of predicted clusters.
Hierarchical clustering of digestive gland microarray data showed two main branches, distinguishing profiles associated with the "hot" months (May August) from the other months.
The microarray results showed that transcription of cluster 6 genes was strongly repressed by HUαβ at all three growth phases analyzed (Fig. 1).
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