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Therefore, a DNA microarray chip of 71 virulence genes of S. typhimurium was developed and evaluated using 10 isolates.
A DNA microarray chip of four virulence genes and 16S ribosomal DNA gene conserved region among all Gram negative species, including Yersinia, as a positive control was developed and evaluated using 22 Yersinia enterocolitica isolates.
Later he joined the lab of molecular biologist Nikki Holbrook and worked with colleagues to construct a DNA microarray chip of 1300 human genes involved in DNA repair, cell suicide, and responses to stress.
Oligonucleotide-array CGH was performed by Nimblegen Inc. using 2-μg of DNA on a microarray chip of 152,452 probes spanning 3.5 mb of chr12p13.31.
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This compendium data set includes 172 Affymetrix microarray chips of platform GPL1261, which contains 45,101 probes.
Microarray chips of the size of histology slides including all known human genes are currently manufactured with high precision.
Using a cell microarray chip for evaluation of the efficacy of antimalarial drugs, more sensitive and high throughput evaluation is anticipated.
The potential of the cell microarray chip for the detection of malaria-infected erythrocytes was shown, it offering 10 100 times higher sensitivity than that of conventional light microscopy and easy operation in 15 min with purified erythrocytes.
In our previous study, we developed a single-cell microarray chip for the analysis of antigen-specific single B-cells [14].
CGH typically involves comparison of the hybridization intensities of genomic DNA samples with microarray chip representations of entire genomes, and has widespread potential application in experimental research and medical diagnostics.
NAT1 is represented on most microarray chips, so interrogation of public databases has revealed changes in NAT1 mRNA levels associated with different cancers and cancer subtypes [ 7].
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