Sentence examples for microarray approach followed from inspiring English sources

In this study, we used a microarray approach followed by substantial technical and biologic validation to identify specific epigenotypes for particular subtypes in breast cancer.

At the molecular level, the frequency of the target-site kdr mutation was investigated and a microarray approach followed by quantitative real-time RT-PCR validation was used to identify detoxification genes putatively involved in metabolic resistance.

This was achieved by the study of gene expression in the adrenal glands under basal conditions and in response to ACTH treatment using a microarray approach followed by validation by quantitative RT-PCR.

After isolating HSCs from liver cancer tissues by using positive markers including OCT3/4, CD133, Nestin, and AFP as well as Carcino-embryonic antigen (CEA), Meng et al. evaluated the miRNA signatures in human HSCs by microarray-based approach followed by the validation with real-time PCR [ 70].

We carried out genome-wide DNA methylation profiling in hearts, livers, and spleens of the MRL/MpJ and C57BL/6J strains using the MeDIP approach followed by microarray analysis.

The loss-of-function approach followed by microarray screen should produce less non-specific side effects and thus lead to more precise profiling of direct and indirect targets.

4. The approach follows the selection criterion of robustness, i.e. technical noise in measured mRNA concentrations caused by the microarray technology does not alter inferred regulatory interactions.

18 Following this exploratory microarray approach, results were validated by quantitative PCR as the gold standard for miRNA quantification.

The use of microarray approach and enzyme activity measurements has allowed us to follow more closely the metabolic changes occurring during starvation.

Moreover, they also ignore the functional association from those functionally related genes in microarray experiments because they assume that biological systems are linear and their approaches follow Normal distribution, respectively.

Application of a high-density oligonucleotide microarray approach to study bacterial population dynamics during uranium reduction and reoxidation.