DLBCL is subclassified into two groups according to microarray analysis: GCB-like DLBCL and ABC-like DLBCL.
PPARβ/δ target genes were recently identified from microarray analysis of human myofibroblast-like cells following either siRNA knockdown of PPARβ/δ or ligand activation of PPARβ/δ in these cells [ 13].
The microarray analysis identified that insulin-like growth factor (IGF -binding proteIGF -binding), which has been reproteinto have a tumour-suppressive activity through the induction of apoptosis in some cancers, was a key gene related to the response to this therapy (Burger et al, 1998; Landberg et al, 2001; Mutaguchi et al, 2003; Sato et al, 2007; Lin et al, 2008; whicheyee et al, 2008).
Importantly, we did not observe significant differences in tumour phenotypes associated with lentiviral transduction, as demonstrated by histological appearance, flow cytometry analysis (see Supplementary Figure S2A and B) and microarray analysis of parental breast CSCs-like and Luc-CSCs-like.
On the other hand, not all triple negative cancers are of basal-like profile, only approximately 85% of ER- and Her2- cancers are classified as basal-like by microarray analysis [ 20].
Because ISH using cancerous tissues, like microarray analysis, can detect antisense expression arising from Thbd (thrombomodulin), there might be more examples of genes for which antisense expression is altered in cancerous tissue but cannot be detected by microarray analysis that targets expression from the sense strand of genes.
Microarray analysis revealed Snail2 expression in basal-like breast cancer cell lines [ 28].
Eager to sort through the pile of curriculum vitae's on his desk, Rudnicki is particularly looking for molecular geneticists working on different stem cell systems; scientists with genomics bents like proteomics, microarray analysis, and bioinformatics; and a couple of clinician scientists.
Yet, the results of our microarray analysis suggest that additional integrins like β5, β6 or β8 might also be involved in altered adhesion to ECM proteins.
In this study, we performed a microarray analysis to observe the human placental trophoblast-like BeWo cells response to lipopolysaccharide (LPS) from periodontopathogen Aggregatibacter actinomycetemcomitans (Aa), in order to investigate the molecular basis of mechanisms for periodontitis-associated LBW.
