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Microarray analysis is commonly based on detection of fluorescence signals through a confocal laser scanner.
Microarray analysis is a powerful tool for examining differences among a very large number of genes rapidly and efficiently; it's the basis for new diagnostic tools, for example, for clinical evaluation of many forms of cancer.
Currently, chromosomal microarray analysis is considered the first-tier test in pediatric care and prenatal diagnosis.
Background: One of the important challenges in microarray analysis is to take full advantage of previously accumulated data, both from one's own laboratory and from public repositories.
Chromosomal microarray analysis is an alternative DNA-based method for interrogating genome-wide CNAs in solid tumors.
Microarray analysis is a powerful technique that can examine the gene expression of thousands of genes simultaneously.
Whole-blood RNA for microarray analysis is easily accessible but contains a large proportion of globin mRNA that interferes with the accurate assessment of other genes.
However, although the genomes of a number of filamentous fungi have been fully or partially sequenced, microarray analysis is still in its infancy in these organisms.
The gene microarray analysis is used to identify a role for CREB in the transcriptional mechanisms that underlie global gene expression in epithelial cells in response to hypoxia.
Chromosomal microarray analysis is standard of care in fetuses with malformations, detecting clinically significant copy number variants in 5 7% of cases over conventional karyotyping.
However, standardization of DNA microarray analysis is needed before it can be used as a routine method for characterizing Salmonella isolates across borders and laboratories.
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