100% of the 27 genes tested by RT-PCR showed similar trends to those observed using microarray analysis, indicating the robustness of our analysis.
These results are in agreement with the microarray analysis indicating that QDs toxicity involves other mechanisms of damage, such as envelope and oxidative stress, among others.
These results are strengthened by microarray analysis, indicating that DS progenitors have a pronounced perturbation, at least at transcriptional level, in the angiogenesis and cell cycle pathways.
Furthermore, eight out of the 25 genes were randomly selected and validated by qRT-PCR analysis with new RNA samples, and the results were in agreement with those of the previous validation and microarray analysis, indicating the reliability of the microarray data.
Thus, LDGs isolated from SLE patients displayed MSI in addition to the copy number alterations and LOH identified by cytogenetic microarray analysis, indicating that genomic alterations associated with DNA strand breaks and replication error are present in LDGs (see Additional file 5).
The results of our microarray analysis indicated that a total of 8410 genes passed the quality control criteria and statistical significance tests to identify genes expressed in adult murine RPE Supplementary Dataa S1).
Additionally, microarray analysis indicated that TGF-β1 up-regulated MAPK signaling in contrast to C-ABC, which did not enrich genetic pathways.
Moreover, microarray analysis indicated that the YAP/TAZ target genes connective tissue growth factor (CTGF), ankyrin repeat domain 1 (ANKRD1), cysteine-rich angiogenic inducer 61 (CYR61), baculoviral IAP repeat containing 5 (BIRC5), AXL receptor tyrosine kinase (AXL), inhibin alpha subunit (INHA) and collagen type VIII alpha 1 chain (COL8A1) are not upregulated in TAM-treated ER-Src cells18.
Microarray analysis indicated that the expressions of testosterone synthesis-associated genes, i.e., Star, P450scc, 3β-Hsd, Abp, Cox7a2, Pcna, p450c17and17β-Hsd were significantly altered by linuron exposure, along with other genes involving in cell proliferation and apoptosis, such as c-myc, S6K, Apaf1, and TSC1.
Microarray analysis indicated that Brahma-related gene 1 (Brg1) and proliferation-related genes including proliferating cell nuclear antigen (Pcna), neurotrophin 3 (Ntf3) and platelet-derived growth factor subunit A (Pdgfα) were significantly downregulated by H2S in endothelin-1-stimulated proliferative vascular smooth muscle cells.
Their microarray analysis indicated 26 genes were up-regulated and 11 genes were down-regulated under dehydration, salinity, and/or cold conditions.
