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DGH reviewed the microarray analysis, generated and curated contig assemblies.
Furthermore, this detailed microarray analysis generated a source of novel molecular targets for the treatment of HPV-associated diseases and potentially of non-HPV neoplasias.
All changes are relative to an internal control, hisD, a gene which previously used as an internal control for semi-quantitative and real-time PCR analysis [ 16, 55] and that was not found to be differentially expressed in any of the microarray analysis generated in this study.
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Since microarray analysis generates vast amounts of data, the resulting data were categorized based on the functional role of each altered transcript.
This approach to microarray analysis generates an outcome with readily interpretable biological meaning.
JDW directed the microarray data analysis, generated GFP reporter lines, scored GFP reporters, compiled Worm Base 170 expression data and helped draft the manuscript.
A microarray based analysis generated a set of 3565 transcripts with at least 2-fold greater expression in females as compared to control males, 1392 such changes were biased during reproductive dormancy.
Probes for microarray analysis were generated from RNA isolated from the proximal colon of 3 control and 3 Hnf4α mutant mice at 12 months of age.
LZ conducted microarray analysis and generated all the mutants.
The heat maps derived from the microarray analysis were generated using the Genesis program [ 90].
KB wrote the algorithm and KB and DW performed the cis-element analysis, JK did the microarray analysis, CW generated reporter constructs and performed transient protoplast transfection experiments.
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