Recently, a genome wide microarray analysis showed that nitrate alone affected the expression of 208 different genes in Arabidopsis thaliana [22].
However, microarray analysis of steady-state mRNA level alone is not sufficient to show whether these genes are directly regulated by MAF1 at the transcriptional level or as the result of downstream secondary effects.
In the present study, we observed through whole genome microarray analysis that the response to Gen alone and in combination with Dex was significantly different from that of E2 or Dex + E2 under the same conditions.
As already discussed, CYP1B1 was strongly up-regulated by BaP in the MCF-7 cells at all time-points and concentrations on the microarrays but in HepG2 cells by RTqPCR analysis alone.
Under these circumstances, co-regulated changes in mRNA levels that depend upon RNA stability alone can be quantified by microarray analysis.
The results reported here represent the first comprehensive microarray analysis to assess the consequences of HPV16 E6 oncoprotein alone in the normal tissue environment from K14E6 transgenic mice.
We performed a systematic search in the PubMed and EMBASE databases in May 2010 using the following search terms alone or in combination: "meningioma", "microarray analysis", "oligonucleotide array sequence analysis", or "gene expression profiling".
We performed DNA microarray analysis (Affymetrix GeneChip) on non-tumorous mucosa obtained from mice that received AOM/DSS, AOM alone, and DSS alone, and untreated mice at wks 5 and 10.
Cultures were exposed to Aβ, the Aβ-Al complex or Al alone and investigated for gene profile changes by microarray analysis, a technique that provides a powerful way to identify novel genes involved in physiopathological signaling cascades.
However, in our microarray analysis we found more differentially expressed genes than expected by chance alone (1,558 observed versus 920 expected).
