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Microarray analyses led to the identification of two genes, CCND1 and CDKN1A, whose expression level is selectively altered in vivo in sFRP1-expressing tumors.
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DNA microarray analyses have led to the identification of novel genes in the BvgA/S regulon, some of which are activated by BvgA/S and others are repressed by BvgA/S.
Similar limitations were inherent within previous homeotic microarray analyses and likely led to the characterization of Apetala1, a sepal and petal expressed transcript [ 28], as expressed in a sepal-specific manner within the previous data set [ 10].
Positive analyses lead to useful innovations.
These analyses lead to two notable findings.
The importance of type I IFNs in lupus pathogenesis has emerged from several observations, led by microarray analyses of gene expression of leukocytes from lupus patients [ 37, 38].
Microarray analyses showed that both compounds led to down- and upregulation of multiple genes (BI8622 2,2677 up, 2,295 down; BI8626: 2,796 up, 2,923 down; cut-off: fold change 2; P < 0.01).
Coupling these phenotypic data with microarray analyses provides loci that may lead to the sterile phenotypic condition of hybrids.
Like for human samples, DNA microarray analyses of xenograft model systems have led to the discovery of several genes associated with cancer progression.
Alternative splicing can lead to altered isoform abundance that may not be apparent from microarray analyses that rely on probing of common exons, or RNA-seq analysis pipelines that only survey gene-level transcription.
This file contains microarray analyses.
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