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The micro domains of P-SPB produced were stable in liquid environment during several weeks and also during AFM imaging.
Three-dimensional RW simulators have been developed to incorporate the discreteness and stochasticity of the signaling in intracellular micro domains.
Activated death receptors localize in distinct lipid raft micro domains in the plasma membrane for efficient formation of death inducing signalling complexes [ 1, 2].
Signaling micro domains are used by the cell to convey information and it is important to use accurate and reliable simulation methods when these processes are studied.
In subcellular micro domains, the number of involved molecules is small and the fluctuations from the predicted average number of molecules involved become dominant.
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Student t-test was used to calculate the p-value, as described previously [59], to determine the statistical difference of molecular density or the percentages of molecules that localized into nano- or micro- domains after different stimulations.
For W = 1.5 μm, we can still observe the strong position dependence; P 1 and P 4 reflect two distinct micro-domains, and the other points can be considered as mixtures of such micro-domains.
In other words, the results of P 1 and P 5 pick up the single configuration of four possible micro-domains shown in Fig. 1c, and the measurement at P 2 and P 4 covers two (or more) micro-domains.
Considering the coherence length, it is expected that such micro-domains contribute to the SHG response incoherently.
Thus merged micro-domains would be critical in the conversion of NGC to GC.
It presents two different micro-domains disorientated with respect to graphene planes by θ1 = ± 19°.
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